Matrilin 4 (MATN4) Rabbit Polyclonal Antibody

CAT#: TA306756

Rabbit Polyclonal MATN4 Antibody

Product Images

Western blot analysis of MATN4 in rat brain tissue lysate with MATN4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of MATN4 in mouse brain tissue with MATN4 antibody at 2.5 ug/ml.

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  Immunofluorescence of MATN4 in mouse brain tissue with MATN4 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MATN4 antibody was raised against a 13 amino acid peptide near the amino terminus of human MATN4.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: matrilin 4
• Database Link:
  NP_085080
  Entrez Gene 8785 Human
  UniProt ID O95460
• Background: Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. Members of the matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil a-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices such as embryonic kidney, lung, bone, cartilage and nervous system. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation. MATN4 could serve as an odontoblast differentiation marker, e.g. in odontoblast stem cell research.
• Synonyms: HE6WCR54