IRF7 Rabbit Polyclonal Antibody
Frequently bought together (3)
Transient overexpression lysate of interferon regulatory factor 7 (IRF7), transcript variant a
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Recombinant protein of human interferon regulatory factor 7 (IRF7), transcript variant a, 20 µg
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Other products for "IRF7"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 0.5 - 1 ug/mL, ICC: 5 ug/mL |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | IRF7 antibody was raised against a peptide corresponding to 14 amino acids near the center of human IRF7. |
Formulation | PBS containing 0.02% sodium azide. |
Concentration | 1ug/ul |
Purification | Affinity chromatography purified via peptide column |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | interferon regulatory factor 7 |
Database Link | |
Background | Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling (3,4). There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established. |
Synonyms | IMD39; IRF-7H; IRF7A; IRF7B; IRF7C; IRF7H |
Reference Data | |
Protein Families | Transcription Factors |
Protein Pathways | Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway |
Documents
Product Manuals |
FAQs |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.