Cbl Goat Polyclonal Antibody
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Other products for "Cbl"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1-3µg/ml. |
Reactivities | Mouse (Expected from sequence similarity: Human, Rat, Dog, Pig, Cow) |
Host | Goat |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Peptide with sequence C-REFVSISSPAHVAT, from the C Terminus of the protein sequence according to NP_005179.2. |
Formulation | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
Concentration | lot specific |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | Casitas B-lineage lymphoma |
Database Link | |
Background | The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq] |
Synonyms | C-CBL; CBL2; RNF55 |
Reference Data |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.