STK39 Rabbit Polyclonal Antibody

CAT#: TA302234

Rabbit Polyclonal Antibody against STK39 (C-term)

Product Images

STK39 Antibody (C-term) (Cat. #TA302234) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the STK39 antibody detected the STK39 protein (arrow).

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  Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with STK39 antibody (C-term) (Cat.#TA302234), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:1000, IHC: 1:10~50
• Reactivities: Human (Predicted: Rat)
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This SPAK (STK39) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human SPAK (STK39).
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 59642 Da
• Gene Name: serine/threonine kinase 39
• Database Link:
  NP_037365
  Entrez Gene 54348 RatEntrez Gene 27347 Human
  UniProt ID Q9UEW8
• Background: STK39 is a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.
• Synonyms: DCHT; PASK; SPAK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase