HCV Envelope glycoprotein E2 Mouse Monoclonal Antibody [Clone ID: 1876]
CAT#: SM2287P
HCV Envelope glycoprotein E2 mouse monoclonal antibody, clone 1876, Purified
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Specifications
Product Data | |
Clone Name | 1876 |
Applications | ELISA, IF, WB |
Recommended Dilution | ELISA. Western Blotting. Immunofluorescence. |
Reactivities | Hepatitis C Virus |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Highly purified Hepatitis C Virus envelope glycoprotein E2 |
Specificity | This antibody is specific for the envelope glycoprotein E2 of Hepatitis C virus (HCV). It has been suggested that HCV infects Human cells through interaction of the E2 envelope glycoprotein and CD81 the putative viral receptor. |
Formulation | PBS containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction. |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Background | Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha. |
Synonyms | Hepatitis C Virus NS1, gp68, gp70 |
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