CD46 Mouse Monoclonal Antibody [Clone ID: MEM-258]

CAT#: SM1819P

CD46 mouse monoclonal antibody, clone MEM-258, Purified

Product Images

Staining of human peripheral blood lymphocytes with MOUSE ANTI HUMAN CD46.

Specifications

Product Data

• Clone Name: MEM-258
• Applications: FC, IP, WB
• Recommended Dilution: Flow cytometry: 1/10 - 1/50; use 10 µl of the suggested working dilution to label 10e6 cells.
  Immunoprecipitation.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: HPB-ALL cell line
• Specificity: This antibody recognises the CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP).
• Formulation: PBS containing 0.09% Sodium Azide
  State: Purified
  State: Liquid purified IgG fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: CD46 molecule
• Database Link:
  Entrez Gene 4179 Human
  UniProt ID P15529
• Background: CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilisation.
• Synonyms: TLX, MIC10