HLA Class II DP, DR, DQ Mouse Monoclonal Antibody [Clone ID: WR18]
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Specifications
Product Data | |
Clone Name | WR18 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 106 cells or 100 µl whole blood. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human HLA Class II (DP, DQ, DR). Spleen cells from an immunised BALB/c mice were fused with cells of the mouse NS0 mouse myeloma cell line. |
Specificity | This antibody recognizes a monomorphic determinant common to DP, DQ and DR beta chains, which are expressed by antigen presenting cells, B cells, monocytes and activated T lymphocytes. |
Formulation | PBS, pH 7.4 containing 0.09% Sodium Azide and 0.1% Bovine Serum Albumin Label: PE State: Lyophilized purified IgG fraction Stabilizer: 0.1% BSA Preservative: 0.09% Sodium Azide Label: R. Phycoerythrin (RPE) |
Reconstitution Method | Restore with 1 ml distilled water |
Purification | Affinity Chromatography on Protein G |
Conjugation | PE |
Storage | Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Stability | Shelf life: one year from despatch. |
Background | The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class II proteins encoded by the HLA which are HLA DP, HLA DQ and HLA DR. |
Synonyms | MHC class II antigen DP, DR, DQ, HLA class II histocompatibility antigen DP, DR, DQ |
Reference Data |
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