ISG15 Mouse Monoclonal Antibody [Clone ID: 2.1]
Other products for "ISG15"
Specifications
Product Data | |
Clone Name | 2.1 |
Applications | WB |
Recommended Dilution | Western blot. Suggested concentration: In our hands good visualization of ISGylated proteins was obtained using an antibody concentration of 1 μg/ml; however, 0.1 μg/ml or lower can be used to give reasonable visualization of the free ISG band. Optimal dilutions should be determined by each laboratory for each application. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human ISG15 |
Specificity | Detects Human ISG15. Detects conjugated and free ISG15. Greater than 95% purity. No cross-reactivity observed with ubiquitin on Western Blot. |
Formulation | 50mM Tris HCl, 75mM NaCl, 50% Glycerol pH 8 State: Purified State: Liquid |
Purification | Protein G purified |
Conjugation | Unconjugated |
Storage | After receipt, this product should be kept at -20°C for retention of full activity. Do not store below -20°C. |
Gene Name | ISG15 ubiquitin-like modifier |
Database Link | |
Background | Many published reports indicate that ISG15 (G1P2) is commonly upregulated in response to Type I interferon stimulation. Though a wide range of cellular activities are influenced by ISG15 expression including Type I interferon signaling, translation, chromatin remodeling, cell motility, protein trafficking, and protein conjugation (ISGylation), the complete spectrum of ISG15-dependent biological sequelae remains to be fully elucidated. Further characterization of new ISG15 target proteins and the role of free ISG15 may offer new insights into mechanistic and immunotherapeutic approaches to human diseases. |
Synonyms | UCRP |
Reference Data |
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