ICAM1 Mouse Monoclonal Antibody [Clone ID: 117G12.02]
Other products for "ICAM1"
Specifications
Product Data | |
Clone Name | 117G12.02 |
Applications | IHC |
Recommended Dilution | ImmunoHistoChemistry frozen sections, ImmunoHistoChemistry paraffin sections. Usage recommendation: *This monoclonal antibody may be used between 1-10 μg/ml. |
Reactivities | Human, Sheep |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | in vitro-derived DCs (GM-CSF+TNF) |
Specificity | mAb 117G2 positively stains sheep tissue sections (Schwartz-Cornil I, pers.communication ; Carlson M.et al, 1988, Nucleic Acids Res. 16 (9): 4188; Yang L. et al, 2005, Blood 106 (2): 584). |
Formulation | 100 μg in 200 μl / 50 μg in 100 μl Tris-NaCl pH 8 State: Purified |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage | -20°C. KEEP CONTENTS STERILE: no preservative. Purified antibodies: avoid repeated freeze/thaw cycles. Coupled antibodies: glycerol protects from freezing. |
Gene Name | intercellular adhesion molecule 1 |
Database Link | |
Background | 117G12 monoclonal antibody was obtained following mouse immunization with in vitro-derived human dendritic cells. The target antigen was found to be CD54/ICAM-1, a cell surface glycoprotein which is typically expressed on endothelial cells and immune cells. CD54/ICAM-1, member of the Ig superfamily, binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also a receptor for rhinovirus. CD54/ICAM-1 is a type of intracellular adhesion molecule, playing a role in transmigration of endothelial cells into tissues through binding to LFA-1. |
Synonyms | ICAM-1 |
Reference Data |
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