Cathepsin L (CTSL) Mouse Monoclonal Antibody [Clone ID: OTI2F1]
CAT#: CF809315
Carrier-free (BSA/glycerol-free) CTSL mouse monoclonal antibody,clone OTI2F1
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI2F1 |
Applications | IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:2000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CTSL (NP_001903) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 35.8 kDa |
Gene Name | cathepsin L |
Database Link | |
Background | The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012] |
Synonyms | CATL; CTSL1; MEP |
Reference Data | |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Antigen processing and presentation, Lysosome |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA809315 | CTSL mouse monoclonal antibody,clone OTI2F1 |
USD 224.00 |
|
TA809315AM | CTSL mouse monoclonal antibody,clone OTI2F1, Biotinylated |
USD 509.00 |
|
TA809315BM | CTSL mouse monoclonal antibody,clone OTI2F1, HRP conjugated |
USD 509.00 |
|
TA809315S | CTSL mouse monoclonal antibody,clone OTI2F1 |
USD 200.00 |
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