DUSP10 Mouse Monoclonal Antibody [Clone ID: OTI3D8]
CAT#: CF806754
Carrier-free (BSA/glycerol-free) DUSP10 mouse monoclonal antibody, clone OTI3D8 (formerly 3D8)
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI3D8 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 180-482 of human DUSP10(NP_009138) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 52.5 kDa |
Gene Name | dual specificity phosphatase 10 |
Database Link | |
Background | Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
Synonyms | MKP-5; MKP5 |
Reference Data | |
Protein Families | Druggable Genome, Phosphatase |
Protein Pathways | MAPK signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA806754 | DUSP10 mouse monoclonal antibody, clone OTI3D8 (formerly 3D8) |
USD 447.00 |
|
TA806754AM | DUSP10 mouse monoclonal antibody, clone OTI3D8 (formerly 3D8), Biotinylated |
USD 509.00 |
|
TA806754BM | DUSP10 mouse monoclonal antibody, clone OTI3D8 (formerly 3D8), HRP conjugated |
USD 509.00 |
|
TA806754S | DUSP10 mouse monoclonal antibody, clone OTI3D8 (formerly 3D8) |
USD 200.00 |
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