Neurofilament (NEFL) Mouse Monoclonal Antibody [Clone ID: OTI11F6]
CAT#: CF801192
Carrier-free (BSA/glycerol-free) NEFL mouse monoclonal antibody, clone OTI11F6 (formerly 11F6)
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI11F6 |
Applications | WB |
Recommended Dilution | WB 1:500 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1-360 of human NEFL (NP_006149) produced in E.coli. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 61.3 kDa |
Gene Name | neurofilament light chain |
Database Link | |
Background | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008] |
Synonyms | CMT1F; CMT2E; NF-L; NF68; NFL; PPP1R110 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
Protein Pathways | Amyotrophic lateral sclerosis (ALS) |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA801192 | NEFL mouse monoclonal antibody, clone OTI11F6 (formerly 11F6) |
USD 224.00 |
|
TA801192AM | NEFL mouse monoclonal antibody,clone 11F6, Biotinylated |
USD 509.00 |
|
TA801192BM | NEFL mouse monoclonal antibody,clone 11F6, HRP conjugated |
USD 509.00 |
|
TA801192S | NEFL mouse monoclonal antibody, clone OTI11F6 (formerly 11F6) |
USD 200.00 |
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