EMA (MUC1) Mouse Monoclonal Antibody [Clone ID: OTI3A7]
CAT#: CF800938
Carrier-free (BSA/glycerol-free) MUC1 mouse monoclonal antibody, clone OTI3A7 (formerly 3A7)
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI3A7 |
Applications | IF, IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human MUC1 (NP_001018016) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 25.1 kDa |
Gene Name | mucin 1, cell surface associated |
Database Link | |
Background | This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011] |
Synonyms | ADMCKD; ADMCKD1; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; SEC |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA800938 | MUC1 (EMA) mouse monoclonal antibody, clone OTI3A7 (formerly 3A7) |
USD 224.00 |
|
TA800938AM | MUC1 mouse monoclonal antibody,clone 3A7, Biotinylated |
USD 509.00 |
|
TA800938BM | MUC1 mouse monoclonal antibody,clone 3A7, HRP conjugated |
USD 509.00 |
|
TA800938S | MUC1 (EMA) mouse monoclonal antibody, clone OTI3A7 (formerly 3A7) |
USD 200.00 |
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