BCL10 Mouse Monoclonal Antibody [Clone ID: OTI1F11]
CAT#: CF800466
Carrier-free (BSA/glycerol-free) BCL10 mouse monoclonal antibody, clone OTI1F11 (formerly 1F11)
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI1F11 |
Applications | WB |
Recommended Dilution | WB 1:2000 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human BCL10 (NP_003912) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 26.1 kDa |
Gene Name | BCL10 immune signaling adaptor |
Database Link | |
Background | This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008] |
Synonyms | c-E10; CARMEN; CIPER; CLAP; IMD37; mE10 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | B cell receptor signaling pathway, T cell receptor signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA800466 | BCL10 mouse monoclonal antibody, clone OTI1F11 (formerly 1F11) |
USD 447.00 |
|
TA800466AM | BCL10 mouse monoclonal antibody,clone 1F11, Biotinylated |
USD 509.00 |
|
TA800466BM | BCL10 mouse monoclonal antibody,clone 1F11, HRP conjugated |
USD 509.00 |
|
TA800466S | BCL10 mouse monoclonal antibody, clone OTI1F11 (formerly 1F11) |
USD 200.00 |
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