BTK Mouse Monoclonal Antibody [Clone ID: OTI3D11]
CAT#: CF501092
Carrier-free (BSA/glycerol-free) BTK mouse monoclonal antibody, clone OTI3D11 (formerly 3D11)
Formulation: Standard
Specifications
Product Data | |
Clone Name | OTI3D11 |
Applications | FC, IF, IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG3 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human BTK (NP_000052) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 76.3 kDa |
Gene Name | Bruton tyrosine kinase |
Database Link | |
Background | The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. |
Synonyms | AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA501092 | Anti-BTK mouse monoclonal antibody, clone OTI3D11 (formerly 3D11) |
USD 447.00 |
|
TA501092AM | Anti-BTK mouse monoclonal antibody, clone OTI3D11 (formerly 3D11), Biotinylated |
USD 509.00 |
|
TA501092BM | Anti-BTK mouse monoclonal antibody, clone OTI3D11 (formerly 3D11), HRP conjugated |
USD 509.00 |
|
TA501092S | Anti-BTK mouse monoclonal antibody, clone OTI3D11 (formerly 3D11) |
USD 200.00 |
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