Desmoglein 2 (DSG2) Mouse Monoclonal Antibody [Clone ID: G96]

CAT#: BM5107

Desmoglein 2 (DSG2) mouse monoclonal antibody, clone G96, Supernatant

Specifications

Product Data

• Clone Name: G96
• Applications: ELISA, IHC, WB
• Recommended Dilution: Western Blot.
  Immunohistochemistry on frozen sections: Ready-to-use; 1 h at RT; preincubation with 0.05 - 0.2% Triton X-100, for 5-10 min, depending on tissue type, is recommended.
  Immunohistochemistry on paraffin sections (enhanced when using the microwave method): Ready-to-use; overnight at 2-8°C.
  ELISA.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant peptide (220aa of 2nd and 3rd extracellular repeat domain)
• Specificity: Antibody recognizes desmoglein 2 present in all epithelia and in tumors derived therefrom as well as in heart muscle and dendritic reticulum cells of lymphatic follicles. In basal epithelial cells desmoglein 2 expression is generally very low.
• Formulation: State: Supernatant
  State: Liquid culture supernatant contains 0.09% NaN3
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C.
  DO NOT FREEZE!
• Stability: Shelf life: one year from despatch.
• Gene Name: desmoglein 2
• Database Link:
  Entrez Gene 1829 Human
  UniProt ID Q14126
• Background: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.
• Synonyms: DSG2, CDHF5,HDGC