UBE4A (Center) Rabbit Polyclonal Antibody

CAT#: AP54445PU-N

UBE4A (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

UBE4A Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35 ug/lane). This demonstrates the UBE4A antibody detected the UBE4A protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1;000.
  Western blot: 1:100~500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 457-486 amino acids from the Central region of human UBE4A
• Specificity: This antibody detects UBE4A (Center).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Potein A column followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: ubiquitination factor E4A
• Database Link:
  Entrez Gene 9354 Human
  UniProt ID Q14139
• Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly.
• Synonyms: Ubiquitin conjugation factor E4 A, KIAA0126
• Note: Molecular Weight: 122561 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis