Nectin 3 (NECTIN3) (C-term) Rabbit Polyclonal Antibody

CAT#: AP53524PU-N

Nectin 3 (NECTIN3) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CD113 / Nectin 3 Antibody (C-term) in MCF-7 cell line lysates (35ug/lane). This demonstrates the PVRL3 antibody detected the PVRL3 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 514-544 amino acids from the C-terminal region of Human CD113 / Nectin 3.
• Specificity: This antibody recognizes Human CD113 / Nectin 3 (C-term).
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: nectin cell adhesion molecule 3
• Database Link:
  Entrez Gene 25945 Human
  UniProt ID Q9NQS3
• Background:
  Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.
• Synonyms: Nectin-3, CDw113, PVRL3, PRR3
• Note: Molecular Weight: 61002 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Adherens junction, Cell adhesion molecules (CAMs)