IL17E (IL25) (Center) Rabbit Polyclonal Antibody

CAT#: AP52193PU-N

IL17E (IL25) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Interleukin-25 / IL25 Antibody (Center) in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the IL25 antibody detected the IL25 protein (arrow).

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  Immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue reacted with Interleukin-25 / IL25 Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunohistochemistry on Paraffin Sections: 1/10-1/50.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 75-104 amino acids from the Central region of Human Interleukin-25 / IL25
• Specificity: This antibody recognizes Human Interleukin-25 / IL25 (Center).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: interleukin 25
• Database Link:
  Entrez Gene 64806 Human
  UniProt ID Q9H293
• Background: The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.
• Synonyms: IL-25, IL17E, IL-17E, Interleukin-17E
• Note: Molecular Weight: 20330 Da

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction