HNF1 beta (HNF1B) (C-term) Rabbit Polyclonal Antibody
CAT#: AP52066PU-N
HNF1 beta (HNF1B) (C-term) rabbit polyclonal antibody, Aff - Purified
Other products for "HNF1 beta"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 505-536 amino acids from the C-terminal region of human HNF1B |
Specificity | This antibody recognizes Human HNF1 beta / TCF2 (C-term). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | HNF1 homeobox B |
Database Link | |
Background | This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene |
Synonyms | HNF-1-beta, HNF-1B, Transcription factor 2, TCF-2, vHNF1, LFB3 |
Note | Molecular Weight: 61324 Da |
Reference Data | |
Protein Families | Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors |
Protein Pathways | Maturity onset diabetes of the young |
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in shipping.