CBX8 (Center) Rabbit Polyclonal Antibody
Other products for "CBX8"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | ELISA: 1/1000. Western blot: 1/100 - 1/500. |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 160-189 amino acids from the Central region of human CBX8 |
Specificity | This antibody reacts to CBX8. |
Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 43396 Da |
Gene Name | chromobox 8 |
Database Link | |
Background | Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
Synonyms | Chromobox protein homolog 8, Polycomb 3 homolog, Rectachrome 1, PC3, RC1 |
Reference Data | |
Protein Families | Transcription Factors |
Documents
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