BHLHA15 (C-term) Rabbit Polyclonal Antibody

CAT#: AP50372PU-N

BHLHA15 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

BHLHA15 Antibody (C-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the BHLHA15 antibody detected the BHLHA15 protein (arrow).

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  BHLHA15 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the BHLHA15 antibody detected the BHLHA15 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 167-197 amino acids from the C-terminal region of human BHLHA15
• Specificity: This antibody reacts to BHLHB8.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: basic helix-loop-helix family member a15
• Database Link:
  Entrez Gene 17341 MouseEntrez Gene 168620 Human
  UniProt ID Q7RTS1
• Background: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity).
• Synonyms: MIST1
• Note: Molecular Weight: 20818 Da

Reference Data

• Protein Pathways: Maturity onset diabetes of the young