TIE1 Rabbit Polyclonal Antibody
Other products for "Tie1"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western Blot: 2-5 μg/ml. |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Highly pure (> 95%) recombinant Mouse soluble TIE-1 (Ser22-Ala748) derived from Insect cells (Cat.-No AR31061PU) |
Specificity | Recognizes Mouse TIE-1 and cross reacts with Human TIE-1 . |
Formulation | PBS, pH 7.2 State: Purified State: Liquid purified IgG fraction |
Reconstitution Method | Restore in sterile water to a concentration of 0.1-1.0 mg/ml. Centrifuge vial prior to opening. |
Purification | Protein A Chromatography |
Conjugation | Unconjugated |
Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 |
Database Link | |
Background | TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. |
Synonyms | TIE, Tie-1 |
Reference Data |
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