TIE1 Rabbit Polyclonal Antibody

CAT#: AP31726PU-N

TIE1 rabbit polyclonal antibody, Purified

Product Images

Western analysis of recombinant Human and Mouse sTIE-1 and sTIE-2 using a Polyclonal antibody directed against Mouse recombinant sTIE-1. There is a strong cross reactivity with Human sTIE-1 but only a weak one for Human and Mouse sTIE-2 visible.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 2-5 μg/ml.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Highly pure (> 95%) recombinant Mouse soluble TIE-1 (Ser22-Ala748) derived from Insect cells (Cat.-No AR31061PU)
• Specificity: Recognizes Mouse TIE-1 and cross reacts with Human TIE-1 .
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified IgG fraction
• Reconstitution Method: Restore in sterile water to a concentration of 0.1-1.0 mg/ml. Centrifuge vial prior to opening.
• Purification: Protein A Chromatography
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
• Database Link:
  Entrez Gene 21846 Mouse
  UniProt ID Q06806
• Background: TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region.
  These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis.
• Synonyms: TIE, Tie-1