NF-kB p65 (RELA) pSer276 Rabbit Polyclonal Antibody
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Other products for "RELA"
Specifications
Product Data | |
Applications | ELISA |
Recommended Dilution | ELISA: 1:500,000 -1:2,000,000, detects the serine 276 phosphorylated NF-κB p65 peptide coated on ELISA plate. |
Reactivities | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide derived from Serine 276 phosphorylated NF-κB p65, conjugated with KLH |
Specificity | Detects Serine 276 phosphorylated NF-κB p65 on Mouse, Human and other species with consensus serine 276 phosphorylated NF-κB p65 peptide (QLRRPSpDRELS). |
Formulation | 0.01M PBS, pH 7.4 State: Azide Free State: Lyophilized Ig fraction |
Reconstitution Method | Restore with double distilled water to adjust the final concentration to 1.00 mg/ml. |
Purification | Protein G affinity purified |
Conjugation | Unconjugated |
Storage | Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | RELA proto-oncogene, NF-kB subunit |
Database Link | |
Background | NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a transcription factor that controls the transcription of many genes that are associated with immuno-response, anti-apoptosis, neuroplasticity and memory. There are five NF-κB proteins in mammals: RelA(NF-κB p65), RelB, c-Rel, NF-κB (NF-κB p105), and NF-κB2 (NF-κB p100). They form a variety of homodimers and heterodimers, each of which activates its own distinctive set of genes. P65 has been shown to be involved with DNA binding Mitogen and stress activated protein kinase phosphorylates NF-κB p65 at serine 276 and controls stem cell factor expression in inflammation. |
Synonyms | NF kappa B p65, NFkB p65, Transcription factor p65, Rel A, NFKB3 |
Reference Data |
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