TrkB (NTRK2) (703-707) Rabbit Polyclonal Antibody
Other products for "TrkB"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western blot: 1:500 - 1:1000. |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Peptide sequence around aa.703~707 derived from TrkB |
Specificity | This antibody detects endogenous levels of total TrkB protein. |
Formulation | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Affinity-chromatography using epitope-specific peptide |
Conjugation | Unconjugated |
Storage | Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | neurotrophic receptor tyrosine kinase 2 |
Database Link | |
Background | Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1. |
Synonyms | TRKB, NTRK2 |
Note | Molecular weight: 145 kDa |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Protein Pathways | MAPK signaling pathway, Neurotrophin signaling pathway |
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