GSTM1 (1-159) Rabbit Polyclonal Antibody

CAT#: AP23586PU-N

GSTM1 (1-159) rabbit polyclonal antibody, Aff - Purified

Product Images

Sample (30 ug of whole cell lysate). A: Hela. 12% SDS PAGE. GSTM1 antibody diluted at 1/1000.

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  Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/500 - 1/3000.
• Reactivities: Bovine, Human, Mouse, Porcine, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 and 159 of Human GSTM1
• Specificity: This antibody reacts to Glutathione S-transferase M1 (GSTM1) at aa 1-159.
• Formulation: 0.1 M Tris-glycine, pH 7.0 containing 20% Glycerol as stabilizer and 0.01% Thimerosal as preservative
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: glutathione S-transferase mu 1
• Database Link:
  Entrez Gene 14862 MouseEntrez Gene 24423 RatEntrez Gene 2944 Human
  UniProt ID P09488
• Background: An enzyme responsible for the metabolism of a broad range of toxic compounds. Mutations are correlated with increased risk of lung cancer after exposure to environmntal tobacco smoke.
• Synonyms: Glutathione S-transferase Mu 1, GST class-mu 1, GSTM1-1, GST1, GSTM1a-1a, GSTM1b-1b, GTH4

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450