KMT2B (2703-2715) Goat Polyclonal Antibody

CAT#: AP22567PU-N

KMT2B (2703-2715) goat polyclonal antibody, Aff - Purified

Product Images

Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with MLL4 antibody followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Testis (formalin-fixed, paraffin-embedded) stained with MLL4 antibody followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/128000.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
• Reactivities: Human, Mouse, Rat, Bovine, Monkey, Porcine, Zebrafish
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from C-term of human MLL4
• Specificity: This antibody detects MLL4 (C-term).
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: lysine methyltransferase 2B
• Database Link:
  Entrez Gene 75410 MouseEntrez Gene 102550344 RatEntrez Gene 9757 Human
  UniProt ID Q9UMN6
• Background: This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.
• Synonyms: WBP7, HRX2, KIAA0304, KMT2D, MLL2, TRX2

Reference Data

• Protein Families: Druggable Genome