H10 (H1F0) Rabbit Polyclonal Antibody

CAT#: AP21050PU-N

H10 (H1F0) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Histone H1 antibody (Cat.-No.: AP21050PU-N)

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  Immunohistochemistry (IHC) analyzes of Histone H1 antibody (Cat.-No.: AP21050PU-N) in paraffin-embedded human colon carcinoma tissue.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
  Immunofluorescence: 1/50-1/200.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Histone H1 protein.
  (region surrounding Pro13)
• Formulation: PBS, pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 31 kDa
• Gene Name: H1 histone family member 0
• Database Link:
  Entrez Gene 14958 MouseEntrez Gene 3005 Human
  UniProt ID P07305
• Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
• Synonyms: H1F0, H1FV, Histone H1', Histone H1(0)

Reference Data

• Protein Families: Druggable Genome