Transglutaminase 2 (TGM2) (Center) Rabbit Polyclonal Antibody

CAT#: AP14652PU-N

Transglutaminase 2 (TGM2) (Center) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of TGM2 (arrow) using rabbit polyclonal TGM2 Antibody (Center). 293 cell lysates (2 ug/lane) either nontransfected (c) or transiently transfected with the TGM2 gene (Lane 2)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human TGM2.
• Specificity: This antibody reacts to Transglutaminase (TGM2).
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: transglutaminase 2
• Database Link:
  Entrez Gene 7052 Human
  UniProt ID P21980
• Background: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.
• Synonyms: TGase C, TGase-H, Tissue transglutaminase