Vinculin (VCL) (C-term) Rabbit Polyclonal Antibody

CAT#: AP14071PU-N

Vinculin (VCL) (C-term) rabbit polyclonal antibody, Purified

Product Images

(LEFT) Western blot analysis of anti-VINC Antibody (C-term) in Ramos cell line lysates (35ug/lane). VINC (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of anti-VINC Antibody (C-term) in mouse lung tissue lysates (35ug/lane). VINC (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blotting: 1/50 - 1/100.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human VINC.
• Specificity: This antibody reacts to VINC.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: vinculin
• Database Link:
  Entrez Gene 7414 Human
  UniProt ID P18206
• Background: VINC is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia.
• Synonyms: Metavinculin