CAMK2D (C-term) Rabbit Polyclonal Antibody
Other products for "CAMK2D"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1/1,000. Western blot: 1/100 -1/500. Immunohistochemistry: 1/50-1/100. |
Reactivities | Human, Monkey |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 448-478 amino acids from the C-terminal region of human CAMK2D (CAMK2 delta). |
Specificity | This antibody detects CAMK2D at C-term. |
Formulation | PBS with 0.09% (W/V) sodium azide State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | calcium/calmodulin dependent protein kinase II delta |
Database Link | |
Background | CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Expression of CAMK2 delta is significantly increased in patients suffering from dilated cardiomyopathy. |
Synonyms | CAMKD, CaM-kinase II delta chain, CaM kinase II subunit delta, CaMK-II subunit delta |
Note | Molecular weight: 56297 Da |
Reference Data |
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