RFC2 (N-term) Rabbit Polyclonal Antibody

CAT#: AP12446PU-N

RFC2 (N-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of anti-RFC2 Antibody (N-term) in K562 cell line lysates (35ug/lane). RFC2 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1,000.
  Western Blot: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human RFC2.
• Specificity: This antibody detects RFC2 (N-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: replication factor C subunit 2
• Database Link:
  Entrez Gene 5982 Human
  UniProt ID P35250
• Background: The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. RFC2 is the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of RFC2 gene has been associated with Williams syndrome.
• Synonyms: Replication factor C subunit 2, Activator 1 subunit 2, RF-C 40 kDa subunit
• Note: Molecular weight: 39157 Da