M6PR (N-term) Rabbit Polyclonal Antibody

CAT#: AP12440PU-N

M6PR (N-term) rabbit polyclonal antibody, Purified

Product Images

Formalin-fixed and paraffin-embedded human testis tissue reacted with M6PR antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: ELISA: 1/1,000.
  Immunohistochemistry: 1/10-1/50.
  Western Blot: 1/1000.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from aa 35-63 on the N-term region of human M6PR.
• Specificity: This antibody detects M6PR (N-term).
• Formulation: PBS with 0.09% (W/V) Sodium Azide as preservative.
  State: Purified
  State: Liquid purified Ig fraction.
• Concentration: lot specific
• Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: mannose-6-phosphate receptor, cation dependent
• Database Link:
  Entrez Gene 4074 Human
  UniProt ID P20645
• Background: M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
• Synonyms: 46 kDa mannose 6-phosphate receptor, MPR46, MPRD, CD Man-6-P receptor, CD-MPR
• Note: Molecular weight: 30993 Da