TLR6 (C-term) Rabbit Polyclonal Antibody

CAT#: AP11536PU-N

TLR6 (C-term) rabbit polyclonal antibody, Purified


USD 580.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution ELISA 1:1,000.
Western blot 1:100 - 1:500.
Immunohistochemistry 1:50 - 1:100.
Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from C-terminal region of human TLR6.
Specificity This antibody detects TLR6 at C-term.
Formulation PBS with 0.09% (W/V) sodium azide
State: Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Conjugation Unconjugated
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name toll like receptor 6
Background TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.
Synonyms Toll-like receptor 6
Note Reacts with mouse in Western blot.
Molecular weight: 91889 Da
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.