RAB11FIP3 Rabbit Polyclonal Antibody
Other products for "RAB11FIP3"
Specifications
Product Data | |
Applications | ELISA, WB |
Recommended Dilution | ELISA: 1/2,000 - 1/10,000. Western Blot: 1/200 - 1/2,000. |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein corresponding to amino acids spanning the carboxyl terminal one-third of human FIP3 |
Specificity | This antibody is directed against FIP3 protein. |
Formulation | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 State: Aff - Purified State: Liquid (sterile filtered) purified Ig fraction Preservative: 0.01% (w/v) Sodium Azide |
Concentration | lot specific |
Purification | Affinity chromatography |
Conjugation | Unconjugated |
Storage | Store the antibody at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | RAB11 family interacting protein 3 |
Database Link | |
Background | Rab11 Family-Interacting Protein 3 (FIP3)/Arfophilin-1 and FIP4/Arfophilin-2 are dual effectors for Rab11 and the ADP-ribosylation factor Arf6. Rab11 and Arf6 are involved in membrane delivery from recycling endosomes to the plasma membrane during cytokinesis. The dual Rab11/Arf6 binding proteins, FIP3 and FIP4, function in the delivery of recycling endosomes to the cleavage furrow and are, together with Rab11, essential for completion of abscission, the terminal step of cytokinesis. An interaction between Rab11-FIP3 and ASAP1 has also been identified (personal communication, P. Randazzo, CCR-NCI, Bethesda, MD). ASAP1 is an Arf GTPase-activating protein that has been implicated in the invasive properties of uveal melanoma and mammary carcinoma. |
Synonyms | Rab11-FIP3, FIP3-Rab11, Arfophilin-1, ARFO1, Eferin, KIAA0665 |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.