ELK1 Rabbit Polyclonal Antibody
Other products for "ELK1"
Specifications
Product Data | |
Applications | IHC, IP, WB |
Recommended Dilution | Western blot: 1/500-1/1000. |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide, corresponding to amino acids 350-400 of Human Elk1. |
Specificity | This antibody detects endogenous levels of ELK1 protein (region surrounding Ser383). |
Formulation | Phosphate buffered saline (PBS), pH 7.2. State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.05% Sodium azide |
Concentration | 1.0 mg/ml |
Purification | Affinity chromatography using epitope-specific immunogen (> 95% pure by SDS-PAGE). |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | ~ 45 kDa |
Gene Name | ELK1, ETS transcription factor |
Database Link | |
Background | Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1–3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element. |
Synonyms | Elk-1 |
Reference Data |
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