DEGS1 Rabbit Polyclonal Antibody

CAT#: AP05308PU-N

DEGS1 rabbit polyclonal antibody, Aff - Purified

Product Images

Immunohistochemical staining of normal human brain tissue using DEGS1 Antibody at 15 ug/ml.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western Blot (1/400 starting dilution).
  Immunohistochemistry (10-15 μg/ml).
  Positive Control: Placenta, normal Human brain.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from the Human DEGS1 protein
• Specificity: This antibody detects Degenerative Spermatocyte Homolog 1.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.08% Sodium Azide
• Concentration: lot specific
• Purification: Antigen Immunoaffiinity Chromatography
• Conjugation: Unconjugated
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: delta(4)-desaturase, sphingolipid 1
• Database Link:
  Entrez Gene 13244 MouseEntrez Gene 58970 RatEntrez Gene 8560 Human
  UniProt ID O15121
• Background: The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.
• Synonyms: DES1, MLD, MIG15, Degenerative spermatocyte homolog 1, Membrane lipid desaturase

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism