prothymosin, alpha (PTMA) Mouse Monoclonal Antibody [Clone ID: 4C3]

CAT#: AM32975PU-N

prothymosin, alpha (PTMA) mouse monoclonal antibody, clone 4C3, Purified

Product Images

The GST tagged recombinant PTMA was loaded at 200 ng/lane. The anti-PTMA clone 4C3 was used at 1 ug/ml and the HRP conjugated goat anti-Mouse IgG was used at 1/2,000 dilution.

Specifications

Product Data

• Clone Name: 4C3
• Applications: ELISA, WB
• Recommended Dilution: ELISA: This antibody is reactive to recombinant PTMA protein.
  Western blot: This antibody is reactive to 38.4KDa GST tagged recombinant PTMA protein.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: A short peptide (eeaengrdapangnan) derived from PTMA was conjugated with KLH for immunization.
• Specificity: This antibody is reactive to PTMA peptide (eeaengrdapangnan) and GST tagged recombinant PTMA protein.
• Formulation: 0.01M PBS, pH 7.0 without preservatives
  State: Purified
  State: Lyophilized purified IgG fraction
• Reconstitution Method: Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml.
• Concentration: 1.0 mg/ml (after reconstitution)
• Purification: Affinity Chromatography on Protein G
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at 2-8°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: prothymosin, alpha
• Database Link:
  Entrez Gene 5757 Human
  UniProt ID P06454
• Background: PTMA (prothymosin alpha) is the precursor of thymosin α1. It is an acidic, non-histone nuclear protein with 109-111 amino acids. PTMA is implicated with cell cycle regulation, chromatin remodeling, expression of oxidative stress-response genes and immunomodulation. PTMA is elevated in malignances such as breast cancer, gastric cancer, prostate and bladder cancers. PTMA is a potential biomarker for the prognosis of cancer treatment.
• Synonyms: PTMA, TMSA, Thymosin alpha-1