DDIT4L (2-98) Mouse Monoclonal Antibody [Clone ID: DDIT-03]
Other products for "DDIT4L"
Specifications
Product Data | |
Clone Name | DDIT-03 |
Applications | FC, WB |
Recommended Dilution | Flow cytometry (intracellular staining). Western blot. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | N-terminal recombinant fragment of human DDIT4L (amino acids 2-98) |
Specificity | This antiobody recognizes DDIT4L / REDD2 protein, which belongs to stress-induced proteins involved in mediation of cell death. |
Formulation | Phosphate buffered saline (PBS) State: Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide, approx. pH 7.4 |
Concentration | lot specific |
Purification | Protein-A affinity chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C. DO NOT FREEZE! |
Stability | Shelf life: one year from despatch. |
Gene Name | DNA damage inducible transcript 4 like |
Database Link | |
Background | DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death. |
Synonyms | DNA-damage-inducible transcript 4-like protein, HIF-1 responsive protein, REDD2, REDD-2, RTP801L |
Reference Data |
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