gamma Adaptin (AP1G1) Mouse Monoclonal Antibody [Clone ID: IMD-113]

CAT#: AM20688PU-N

gamma Adaptin (AP1G1) mouse monoclonal antibody, clone IMD-113, Purified

Specifications

Product Data

• Clone Name: IMD-113
• Applications: WB
• Recommended Dilution: Western Blot: 2 - 4 μg/ml.
• Reactivities: Human, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: AP-1 adaptor from bovine brain.
• Specificity: This antibody reacts to AP1 complex subunit gamma-1.
• Formulation: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
  State: Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% sodium acetate or neutral PBS
• Concentration: 0,1 mg/ml (after reconstitution with PBS)
• Purification: Affinity chromatography
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for one month
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: adaptor related protein complex 1 gamma 1 subunit
• Database Link:
  Entrez Gene 171494 RatEntrez Gene 164 Human
  UniProt ID O43747
• Background: Adaptins are important components of heterotetrameric adaptor complexes (APs) whose role is to promote the formation of clathrin-coated pits and vesicles. The AP-1 adaptor, localized at the trans-Golgi network, is composed of 2 approximately 100-kD subunits, beta-prime-adaptin and gamma-adaptin. The predicted 825-amino acid protein shares 99% identity with mouse gamma-adaptin. Northern blot analysis revealed that gamma-adaptin was expressed as a 7.5-kb transcript in all human tissues tested. Human gamma-adaptin gene (ADTG) is assigned to 16q23.
• Synonyms: ADTG, CLAPG1, gamma 1 Adaptin, gamma Adaptin

Reference Data

• Protein Pathways: Lysosome