Tryptophan Hydroxylase (TPH1) Mouse Monoclonal Antibody [Clone ID: Try-63]
CAT#: AM20674PU-N
Tryptophan Hydroxylase (TPH1) mouse monoclonal antibody, clone Try-63, Purified
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Specifications
Product Data | |
Clone Name | Try-63 |
Applications | WB |
Recommended Dilution | Western Blot: 0.5 - 1 μg/ml. |
Reactivities | Human, Rabbit, Rat |
Host | Mouse |
Isotype | IgG3 |
Clonality | Monoclonal |
Immunogen | Recombinant rabbit tryptophan hydroxylase |
Specificity | This antibody reacts to Tryptophan 5-hydroxylase 1. |
Formulation | 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative State: Purified State: Lyphilized purified Ig fraction |
Reconstitution Method | Restore with 1.2% sodium acetate or neutral PBS |
Concentration | 0,1 mg/ml (after reconstitution with PBS) |
Purification | Affinity chromatography |
Conjugation | Unconjugated |
Storage | Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | tryptophan hydroxylase 1 |
Database Link | |
Background | Tryptophan hydroxylase is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine,or 5HT). Tryptophan hydroxylaseatalyzes the iopterin-dependent monooxygenation of tryptophan to5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Human tryptophan hydroxylase (TPH) is mapped to chromosome 11p15.3-p14 by in situhybridization. |
Synonyms | Tryptophan 5-monooxygenase 1, TPRH, TRPH |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Tryptophan metabolism |
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