HPRT (HPRT1) Mouse Monoclonal Antibody [Clone ID: AT2G8]
Other products for "HPRT"
Specifications
Product Data | |
Clone Name | AT2G8 |
Applications | ELISA, WB |
Recommended Dilution | ELISA. Western blot (1/500-1/5000). Recommended starting dilution is 1/1000. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Recombinant human HPRT (1-218aa) purified from E. coli |
Specificity | The antibody recognizes Human HPRT. Other species not tested. |
Formulation | PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein-G affinity chromatography |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | hypoxanthine phosphoribosyltransferase 1 |
Database Link | |
Background | HPRT is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. HPRT, which acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP, functions primarily to salvage purines from degraded DNA to renewed purine synthesis. |
Synonyms | HGPRTase, HGPRT |
Reference Data | |
Protein Families | Druggable Genome, Stem cell - Pluripotency |
Protein Pathways | Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
Documents
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