Growth Hormone (GH1) Mouse Monoclonal Antibody [Clone ID: YC8]

CAT#: AM09304HR-N

Growth Hormone (GH1) mouse monoclonal antibody, clone YC8, HRP

Specifications

Product Data

• Clone Name: YC8
• Applications: ELISA
• Recommended Dilution: ELISA: This HRP-conjugated monoclonal antibody can be used as a Tracer/Detection Antibody in Sandwich ELISA applications for hGH detection in combination with a Capture Antibody Cat.-No DM1015.
  Suggested Capture Coating Dose: 0.3 μg/ml (Substrate: TMB).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified Recombinant hGH
• Specificity: This monoclonal antibody reacts with natural and recombinant hGH.
• Formulation: 0.01M PBS, pH 7.0 ± 0.1 in 50% Glycerol and 0.01% thimerosal as a bacteriostat
  Label: HRP
  State: Liquid purified IgG fraction
  Label: Horseradish Peroxidase
• Purification: Affinity Chromatography on Protein G
• Conjugation: HRP
• Storage:

  Store (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: growth hormone 1
• Database Link:
  Entrez Gene 2688 Human
  UniProt ID P01241
• Background: Human growth hormone (hGH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. The effects of hGH in the body can be generally described as anabolic. It stimulates amino acid uptake and protein synthesis in muscle and other tissues.
  Growth Hormone (GH1) is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Genes for growth hormone (GH) are found in a gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. The GHN1 gene is transcribed exclusively in the pituitary, whereas the other 4 genes are expressed only in placental tissues. Several isoforms of GH1 exist.
• Synonyms: Pituitary growth hormone, Growth hormone 1, HGH

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction