LITAF Mouse Monoclonal Antibody [Clone ID: AT5C10]

CAT#: AM09081PU-S

LITAF mouse monoclonal antibody, clone AT5C10, Purified

Product Images

Cell lysates of HeLa (20ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human LITAF (1:2000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

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  Western blot analysis: Cell lysates of HeLa (20 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human LITAF (1:2000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Product Data

• Clone Name: AT5C10
• Applications: ELISA, FC, WB
• Recommended Dilution: ELISA.
  Western blot (1/2000-1/3000).
  Flow CYtometry.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Recombinant human LITAF (1-161 aa) purified from E. coli
• Specificity: The antibody recognizes Human LITAF.
  Other species not tested.
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein-G affinity chromatography
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: lipopolysaccharide induced TNF factor
• Database Link:
  Entrez Gene 9516 Human
  UniProt ID Q99732
• Background: Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF) mediates the expression of inflammatory cytokines such as TNF-alpha in Lipopolysaccharide-induced processes. LITAF binds to STAT6B, a member of the STAT6 family forming a complex on the TNF-alpha promoter that modulates TNF activity. High levels of expression of LITAF mRNA have been observed predominantly in the placenta, peripheral blood leukocytes, lymph nodes and spleen.
• Synonyms: LITAF, PIG7, SIMPLE, LPS-induced TNF-alpha factor, p53-induced gene 7 protein

Reference Data

• Protein Families: Druggable Genome, Transcription Factors