GLUR3 (GRIA3) Mouse Monoclonal Antibody [Clone ID: 1D2]

CAT#: AM06645SU-N

GLUR3 (GRIA3) mouse monoclonal antibody, clone 1D2, Ascites

Product Images

Western blot analysis using GRIA3 mAb against HEK293 (1) and GRIA3 (AA: 683-824)-hIgGFc transfected HEK293 (2) cell lysate.

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  Red: Control Antigen (100ng) Purple: Antigen (10ng) Green: Antigen (50ng) Blue: Antigen (100ng)

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  Immunohistochemical analysis of paraffin-embedded human brain tissues (left) and rat brain tissues (right) using GRIA3 mouse mAb with DAB staining.

Specifications

Product Data

• Clone Name: 1D2
• Applications: ELISA, IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.
  Immunohistochemistry on paraffin sections: 1/200 - 1/1000.
  ELISA: 1/10000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of human GRIA3 expressed in E. Coli.
  
• Specificity: This antibody reacts to GRIA3.
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% sodium azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 101 kDa
• Gene Name: glutamate ionotropic receptor AMPA type subunit 3
• Database Link:
  Entrez Gene 2892 Human
  UniProt ID P42263
• Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
• Synonyms: GluR-3, GluR-C, GluR-K3, Glutamate receptor ionotropic AMPA3, GRIA3, GLURC, GluA3