IKB beta (NFKBIB) Mouse Monoclonal Antibody [Clone ID: 7B4]

CAT#: AM06491SU-N

IKB beta (NFKBIB) mouse monoclonal antibody, clone 7B4, Ascites

Product Images

Western blot analysis using NFKBIB antibody Cat.-No AM06491SU-N against Jurkat (1) cell lysate.

Specifications

Product Data

• Clone Name: 7B4
• Applications: ELISA, WB
• Recommended Dilution: ELISA: 1/10000.
  Western Blot: 1/500 - 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human NFKBIB expressed in E. Coli.
• Specificity: Recognizes NFKBIB / IKBB
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 45 kDa
• Gene Name: NFKB inhibitor beta
• Database Link:
  Entrez Gene 4793 Human
  UniProt ID Q15653
• Background: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.
• Synonyms: I-kappa-B-beta, TRIP9, IkB-B, IkB-beta, IkappaBbeta, TR-interacting protein 9