MSH6 Mouse Monoclonal Antibody [Clone ID: 3A10H7]

CAT#: AM06411SU-N

MSH6 mouse monoclonal antibody, clone 3A10H7, Ascites

Product Images

Western blot analysis using MSH6 antibody Cat.-No AM06411SU-N against truncated MSH6 recombinant protein.

Specifications

Product Data

• Clone Name: 3A10H7
• Applications: ELISA, WB
• Recommended Dilution: ELISA: 1/10000.
  Western Blot: 1/500 - 1/2000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of MSH6 expressed in E. Coli.
• Specificity: Recognizes MSH6
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: mutS homolog 6
• Database Link:
  Entrez Gene 2956 Human
  UniProt ID P52701
• Background: Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.
• Synonyms: DNA mismatch repair protein Msh6, GTBP