CD20 (MS4A1) Mouse Monoclonal Antibody [Clone ID: 3E9D3C1G3]

CAT#: AM06197SU-N

CD20 (MS4A1) mouse monoclonal antibody, clone 3E9D3C1G3, Ascites

Product Images

Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using CD20 antibody

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  Immunofluorescence analysis of B lymphocytes using CD20 antibody

Specifications

Product Data

• Clone Name: 3E9D3C1G3
• Applications: ELISA, IF, IHC
• Recommended Dilution: ELISA: 1/10000.
  Immunofluorescence: 1/200 - 1/1000.
  Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: KLH conjugated Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of Human CD20
• Specificity: Recognizes MS4A1/CD20.
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: membrane spanning 4-domains A1
• Database Link:
  Entrez Gene 931 Human
  UniProt ID P11836
• Background: CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.
• Synonyms: MS4A1, Leu-16, Bp35, B-cell marker