IL10 Mouse Monoclonal Antibody [Clone ID: 3C12C12]

CAT#: AM06081PU-N

IL10 mouse monoclonal antibody, clone 3C12C12, Purified

Product Images

Western blot analysis using IL10 antibody Cat.-No AM06081PU-N against IL10 recombinant protein.

Specifications

Product Data

• Clone Name: 3C12C12
• Applications: ELISA, WB
• Recommended Dilution: Western Blot: 1/500 - 1/2000.
  ELISA: 1/10000.
  
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of Human IL-10 expressed in E. Coli.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.03% Sodium Azide
• Conjugation: Unconjugated
• Storage:
  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: interleukin 10
• Database Link:
  Entrez Gene 3586 Human
  UniProt ID P22301
• Background: Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
• Synonyms: IL-10, CSIF, TGIF