CD8A Mouse Monoclonal Antibody [Clone ID: CC63]
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Specifications
Product Data | |
Clone Name | CC63 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 10e6 cells in 100 µl. |
Reactivities | Bovine, Goat, Sheep |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Specificity | This antibody reacts with the CD8 antigen expressed by a subset of T lymphocytes. The antibody precipitates molecules of 34kD and 38kD under reducing conditions. |
Formulation | Phosphate buffered saline 0.09% Sodium Azide, 1% Bovine Serum Albumin Label: PE State: Lyophilized Ig fraction Label: R. Phycoerythrin (RPE) |
Reconstitution Method | Reconstitute with 1 ml distilled water. |
Purification | Affinity chromatography on Protein G |
Conjugation | PE |
Storage | Prior and following reconstitution store undiluted at 2-8°C. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
Stability | Shelf life: One year from despatch. |
Database Link | |
Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. |
Synonyms | CD8 alpha chain, CD8A, MAL |
Reference Data |
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